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Welcome to the Centre for Modeling Human Disease (CMHD) Gene Trap Resource – the PolyA Trap Resource of the International Gene Trap Consortium (IGTC)

The CMHD Gene Trap Resource is directed by Professor Bill Stanford of the University of Toronto in Canada. Our resource features the use of complementary second and third generation polyA trap vectors developed by the Stanford lab and the laboratory of Professor Yasumasa Ishida of the Nara Institute of Science and Technology (NAIST) in Japan to mutagenize murine embryonic stem (ES) cells.

Our current goals are to generate gene trap insertions using mutagenic polyA trap vectors, followed by sequence tagging to develop a library of mutagenized ES cells freely available to the scientific community. This library is searchable by sequence or key word searches including gene name or symbol, chromosome location, or Gene Ontology (GO) terms. In addition, we offer a custom email alert service in which researchers are able to submit search criteria. Researchers will receive automated e-mail notification of matching gene trap clones as they are entered into the library and database.


General inquiries should be directed to Lauryl Nutter at

Questions regarding CMHD Gene Trap resource should be directed to:

Dr. William L. Stanford, Ph.D.
Canada Research Chair in Stem Cell Biology & Functional Genomics
Associate Professor & Associate Chair
Institute of Biomaterials & Biomedical Engineering, University of Toronto
Director, Gene Trap Mutagenesis, Centre for Modeling Human Disease
164 College Street, Room 407
Toronto, ON M5S 3G9 CANADA

Office: (416) 946-8379
Lab: (416) 946-3835
Fax: (416) 978-4317
Lab website:


Mount Sinai Hospital